Our laboratory is interested how
retinal ganglion cells and their axons interact with the cellular
and molecular environment of the optic nerve in the settings of
trauma and disease. Specific research areas include:
1) Retinal axon responses and survival in the optic nerve following
acute trauma and chronic progressive injury.
2) Novel methods for axon repair utilizing micro and nanotechnology platforms.
Research studies are conducted using various mouse models of traumatic
CNS, PNS injury and glaucomatous optic neuropathy. Methodologies
include microscale cell culture, time-lapse microscopy, in vivo
manipulations, thin film neuronal micropatterning, microfabricated
surgical devices, and microfluidics.
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