In 1999 ARVO (Association for Research in Vision and Ophthalmology) held its Annual Meeting in Fort Lauderdale, Florida, May 4 – 7. The following physicians and scientists of the UCSF Department of Ophthalmology, Beckman Vision Center, presented papers at the four-day conference, including:

Richard L. Abbott, MD
Refractive Surgery I. 12 Month Summary of the ICRSr PMA Cohort for the Treatment of Myopia. Phase II and Phase III Study Group

Jorge A. Alvarado, MD

Trabecular Meshwork III. ZO-1 and TIGR Expression in Human Trabecular Meshwork Cells

Susan R. Carter, MD

Orbit and External Eye Disease. Cyanoacrylate Tissue Adhesive in CO2 Laser Blepharoplasty

Emmett T. Cunningham, Jr., MD, PhD, MPH
Uveitis: Clinical Aspects. The Diagnostic Importance of Elevated Intraocular Pressure in Patients with Acute Uveitis • Tumors, Misc. Retinal Research II. Retinal Edema in Patients with Acute Zonal Occult Outer Retinopathy

Emmett T. Cunningham, Jr., MD, PhD, MPH, and Todd P. Margolis, MD, PhD

Clinical Uveitis II. Subretinal Fibrosis as a Long-term Complication of Vogt-Koyanagi-harada Syndrome

David G. Hwang, MD and Todd P. Margolis, MD, PhD
Herpes and Adenovirus: Pathogenesis, Diagnosis, Treatment. A Cell Culture Model for Hsv Endotheliitis

David G. Hwang, MD
Corneal Aberrations and Quality of Vision after Refractive Surgery II. Size Matters: The Effective Optical Zone and Visual Performance after Keratorefractive Surgery • Amniotic Membrane Transplantation and Corneal Equivalents. Indentification of Anti-Neovascularization Proteins in Human Amniotic Membrane • Corneal Stroma. Effects of Method of Corneal De-Epithelialization on Keratocyte Loss and Inflammation after Excimer Laser Keratectomy • Epithelial Repair. Immunolocalization of Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinase in a Rat Model of Cauterization-Induced Corneal Neovascularization

Matthew M. LaVail, PhD

Erg: Animal Studies and Genetic Manipulations. Functional Abnormalities in the Nervous Mutant Mouse • Retinal Cell Death and Apoptosis: Models and Mechanisms. Rhodopsin Concentration and Distribution in Normal and Transgenic Rats with a Mutant Opsin Gene • Photoreceptor Apoptosis: Regulation and Mechanisms. Quantitative Trait Loci in the Mouse Influence the Severity of Light Damage • Optic Nerve Experimental I. Housing in Low Level, Constant Light Stabilizes Circadian Intraocular Pressure (IOP) Oscillations in Brown Norway Rats, Simplifying a Glaucomatous Neuropathy Model

Stephen D. McLeod, MD

Bugs and Drugs. The Effect of Topical Trovafloxacin in a Rabbit Streptococcus Pneumoniae Keratitis Model

Todd P. Margolis, MD, PhD

AIDS: Pathogenesis, Diagnosis, and Treatment of CMV Retinitis. Prevalence of CMV UI97 Resistance Mutations in the Eyes of Patients with Aids and Newly Diagnosed CMV Retinitis

Thai D. Nguyen, PhD

Trabecular Meshwork II. Studies of Tigr Protein Expression and Secretion in Tm Cells using Fluorescent-tagged Protein • Genetics in Glaucoma II. Identification of a TIGR Gene Mutation in Random POAG Patients in Guatamala • Trabecular Meshwork II. Quantification of TM and SC Cell TIGR Response to Dexamethasone (DEX)

Thai D. Nguyen, PhD, and Jon R. Polansky, MD, PhD

Trabecular Meshwork I. Assembly of Fibronectin/TIGR Matrices in Human Trabecular Meshwork (HTM) Cells • Genetics in Glaucoma III. Evidence for Homoallelic Complementation as a Model to Account for the Unaffected Status of Homozygotes Carrying an Autosomal Dominant TIGR Mutation

Joan M. O’Brien, MD

Chemoprophylaxis for High Risk Factors on Histopathologic Examination of Retinoblastoma Eyes • Efficacy of the Differentiating Agent Sodium Butyrate in a Murine Transgenic Model of Retinoblastoma •
In Vitro Efficacy of Combined Carboplatin, Etoposide, and/or Vincristine with and without Hyperthermia in Transgenic Murine Retinoblastoma.

Jon R. Polansky, MD, PhD

Trabecular Meshwork II. Latrunculin (LAT) - Effects on Human Trabecular Meshwork (HTM) Cells • Genetics in Glaucoma III. Herpes Simplex Virus (HSV)-1 Mediated Gene Transfer to Primate Ocular Tissues • Glaucoma Pharmacology, Cellular Mechanism II. Tigr Protein is Reduced in the Ciliary Muscle of Prostaglandin-Treated Monkey Eyes

Daniel M. Schwartz, MD
Biochemistry and Molecular Biology of Retina and RPE. Regulation of Lipid Uptake by Cultured Human Retinal Pigment Epithelium Cells • Uveitis Pharmacology. Toxicity of Intraocular Hyaluronidase

Robert l. Stamper, MD

Glaucoma Clinical Research I. Incidence of Blebitis or Endophthalmitis Associated with Bleb Leaks Following Mmc Filtration Surgery

John P. Whitcher, MD, MPH, and Douglas S. Holsclaw, MD

Autoimmune Diseases of the Eye. Clinical Studies: The Prevalence of Bacterial Pathogens on the Lids and Conjunctiva and the Incidence of Corneal Ulceration in Ocular Cicatrical Pemphigoidr gifted young scientists, and unrestricted grants to the department for numerous research efforts.